RefPrimeCouch—a reference gene primer CouchApp

RefPrimeCouch—a reference gene primer CouchApp

To support a quantitative real-time polymerase chain reaction standardization project, a new reference gene database application was required. The new database application was built with the explicit goal of simplifying not only the development process but also making the user interface more responsive and intuitive. To this end, CouchDB was used as the backend with a lightweight dynamic user i...

A Reference Architecture Primer

A Reference Architecture captures the essence of the architecture of a collection of systems. The purpose of a Reference Architecture is to provide guidance for the development of architectures for new versions of the system or extended systems and product families. We provide guidelines for the content of a Reference Architecture and the process to create and maintain it. A Reference Architect...

Primer on the Gene Ontology.

The Gene Ontology (GO) project is the largest resource for cataloguing gene function. The combination of solid conceptual underpinnings and a practical set of features have made the GO a widely adopted resource in the research community and an essential resource for data analysis. In this chapter, we provide a concise primer for all users of the GO. We briefly introduce the structure of the ont...

A Primer on Gene Patents amsa

Nucleic Acid–based Strategies for Perturbing Gene Expression—a Primer

AS WE APPROACH the new millennium, a quick glance backwards reveals that truly astounding progress has been made in the identification of genes responsible for cell growth, development, and neoplastic transformation. With this knowledge has come a natural desire to ‘‘translate’’ this information into new therapeutic strategies for many of the common maladies that afflict humankind. These includ...